TREATMENT OF PERSISTENT GLAUCOMA SECONDARY TO PERIOCULAR CORTICOSTEROIDS

PURPOSE: To describe two patients with uveitis who developed increased intraocular pressure that was unresponsive to maximum medical therapy eight and 13 months after periocular injection of triamcinolone aceto nide. METHODS: Excised periocular tissue was analyzed for corticostero id activity by gas chromatography and mass spectrometry. RESULTS: Exci sion of the periocular tissue, which contained visible triamcinolone a cetonide, result ed in a normal intraocular pressure within 14 days. i n both patients. Analysis of the excised tissue disclosed residual cor ticosteroid in one of the two patients. CONCLUSION: Removal of periocu lar tissue containing injected corticosteroids may facilitate the mana gement of patients developing increased intraocular pressure unrespons ive to maximum medical therapy.