APPLICATION OF ORGANOLITHIUM AND RELATED REAGENTS IN SYNTHESIS .18. SYNTHETIC STRATEGIES BASED ON AROMATIC METALATION - A CONVERSION OF METHYL ORTHO-PYRIDOYLBENZOATES INTO AZA-ANTHRA-5,10-QUINONES

Authors
EPSZTAJN J JOZWIAK A KRYSIAK JK LUCKA D
Citation
J. Epsztajn et al., APPLICATION OF ORGANOLITHIUM AND RELATED REAGENTS IN SYNTHESIS .18. SYNTHETIC STRATEGIES BASED ON AROMATIC METALATION - A CONVERSION OF METHYL ORTHO-PYRIDOYLBENZOATES INTO AZA-ANTHRA-5,10-QUINONES, Tetrahedron, 52(33), 1996, pp. 11025-11036
Citations number
48
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
52
Issue
33
Year of publication
1996
Pages
11025 - 11036
Database
ISI
SICI code
0040-4020(1996)52:33<11025:AOOARR>2.0.ZU;2-G
Abstract
The synthesis of the aza-anthraquinones (16) and (17) via metallation (LDA / THF) of the pyridine nucleus at the C-3-carbon atom of the meth yl ortho-pyridinecarbonyl benzoates (12) and (13), and then the intram olecular cross addition of the generated lithiated species to the carb omethoxy group is described. Copyright (C) 1996 Elsevier Science Ltd