STUDIES OF THE NEW HERBICIDE KIH-6127 .2. SYNTHESIS AND HERBICIDAL ACTIVITY OF 6-ACYL PYRIMIDIN-2-YL SALICYLATES AND ANALOGS AGAINST BARNYARD GRASS

The method reported previously (Part I) was employed to prepare a vari ety of novel 6-acylsalicylates as key intermediates. 6-Acylpyrimidin-2 -yl salicylates (2-acyl-6-[(4,6-disubstituted pyrimidin-2-yl)oxy]benzo ate derivatives: Type 1), the closely related phthalide compounds lkyl -7-[(4,6-dimethoxypyrimidin-2-yl)oxy]phthalide derivatives: Type 2) an d the ketal derivatives of acyl-6-[(4,6-dimethoxypyrimidin-2-yl)oxy]be nzoates (Type 3) were synthesized and their herbicidal activities meas ured. Methyl cetyl-6-[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate gave e xcellent control of barnyard grass with a promising profile as a proto type rice herbicide.