Xh. Wang et al., L-MALIC ACID PRODUCTION FROM FUMARIC-ACID BY A LABORATORY SACCHAROMYCES-CEREVISIAE STRAIN SHY2, Biotechnology letters, 18(12), 1996, pp. 1441-1446
L-Malic acid was produced efficiently from fumaric acid by Saccharomyc
es cerevisiae SHY2. The amount of L-malic acid produced increased with
the increase in initial fumaric acid concentration (from 20 to 120 g/
L). The average specific and volumetric production rates reached up to
0.708 g/g . h and 2.787 g/L . h, respectively, in 24 hours. Final L-m
alic acid concentration of up to 109 g/L was obtained in 96 hours.