For more than 2 centuries, the nature and pathophysiology of pharyngoe
sophageal (Zenker's) diverticulum has been a matter of argument, The i
ntrinsic or extrinsic forces and structures that might play a role in
the development of this disorder have been repeatedly scrutinized, and
still today the different theories of muscular incoordination and/or
spasm, cricopharyngeal achalasia, gastroesophageal reflux, or neuromus
cular abnormalities try to find their way as the final word regarding
etiology remains to be told, Options for treatment follow a similar pa
ttern although myotomy and diverticulopexy seem to have yielded the be
st results, In this review, historical and current data gathered from
the world literature are compiled in an attempt to give a clear overvi
ew of the pathophysiology surrounding the genesis of Zenker's divertic
ulum and the clinical manifestations, diagnosis, and different alterna
tives for definite treatment of this disorder.