CHANGES IN LIPID-PEROXIDATION, SUPEROXIDE-DISMUTASE ACTIVITY, ASCORBIC-ACID AND PHOSPHOLIPID CONTENT IN LIVER OF FRESH-WATER CATFISH HETEROPNEUSTES-FOSSILIS EXPOSED TO ELEVATED-TEMPERATURE

1. Lipid peroxidation, superoxide dismutase (SOD) activity, ascorbic a cid (AsA) and individual phospholipid contents in liver of fresh water cat fish Heteropneustes fossilis were measured after exposure to diff erent temperatures (25, 27, 32, 37 degrees C) at various times (1-4 h) . 2. Lipid peroxidation and superoxide dismutase activity were signifi cantly increased with increases in temperature at various times. 3. As corbic acid content was depleted when temperature was increased. 4. Af ter temperature exposure, phosphatidyl inositol was increased while ph osphatidyl choline, phosphatidyl serine and phosphatidyl ethanolamine were depleted. Phosphatidic acid level did not change. 5. The findings indicated an increased oxidative stress in liver following increases in temperature at various times. Concurrent with the increase in lipid peroxidation, superoxide dismutase activity and ascorbic acid from th e liver of fish varied. It is suggested that depletion of major indivi dual phospholipids following temperature exposure could be due to supe roxide created oxidative stress in the liver. Copyright (C) 1996 Elsev ier Science Ltd.