CHIRAL LIGANDS DERIVED FROM ABRINE .3. ASYMMETRIC PICTET-SPENGLER REACTION OF ABRINE METHYL-ESTER AND SYNTHESIS OF CHIRAL 1,2,3,4-TETRAHYDRO-BETA-CARBOLINES AS PROMOTERS IN ADDITION OF DIETHYLZINC TOWARD AROMATIC-ALDEHYDES

Authors
DAI WM ZHU HJ HAO XJ
Citation
Wm. Dai et al., CHIRAL LIGANDS DERIVED FROM ABRINE .3. ASYMMETRIC PICTET-SPENGLER REACTION OF ABRINE METHYL-ESTER AND SYNTHESIS OF CHIRAL 1,2,3,4-TETRAHYDRO-BETA-CARBOLINES AS PROMOTERS IN ADDITION OF DIETHYLZINC TOWARD AROMATIC-ALDEHYDES, Tetrahedron letters, 37(33), 1996, pp. 5971-5974
Citations number
41
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
33
Year of publication
1996
Pages
5971 - 5974
Database
ISI
SICI code
0040-4039(1996)37:33<5971:CLDFA.>2.0.ZU;2-J
Abstract
Asymmetric Pictet-Spengler reaction of a number of aldehydes with Abri ne methyl ester (1) was performed at room temperature to furnish mainl y 3 and high ee was obtained in enantioselective addition of Et(2)Zn w ith PhCHO catalyzed by chiral 1,2,3,4-tetrahydro-beta-carboline deriva tives 5 synthesized from 3. Copyright (C) 1996 Elsevier Science Ltd