5-FORMYL SALICYLALDEHYDE AS A LINKER FOR THE SYNTHESIS OF BENZOFURAN CONTAINING INSULIN SENSITIVITY ENHANCER COMPOUNDS

Authors
STILLE JR WARD JA LEFFELMAN C SULLIVAN KA
Citation
Jr. Stille et al., 5-FORMYL SALICYLALDEHYDE AS A LINKER FOR THE SYNTHESIS OF BENZOFURAN CONTAINING INSULIN SENSITIVITY ENHANCER COMPOUNDS, Tetrahedron letters, 37(52), 1996, pp. 9267-9270
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
52
Year of publication
1996
Pages
9267 - 9270
Database
ISI
SICI code
0040-4039(1996)37:52<9267:5SAALF>2.0.ZU;2-V
Abstract
5-Formyl salicylaldehyde was prepared by treatment of 4-hydroxybenzald ehyde with HMTA in TFA. Reaction of this dialdehyde with alpha-haloace tyl aryl compounds gave 2,5-disubstituted benzofurans, from which an I nsulin Sensitivity Enhancer compound was prepared. Copyright (C) 1996 Elsevier Science Ltd