Objective: To measure transcription and analytical errors made by Aust
ralian chemical pathology laboratories. Design: Retrospective data col
lection covering the period 1 November 1993 to 1 April 1994. Setting a
nd participants: Fourteen pathology laboratories in five Australian St
ates (seven in the public sector, and seven in the private sector). Ma
in outcome measures: Error rates in transcribing information from requ
est forms to computer record systems, and laboratory performance on ch
emical analysis. Results: Pathology laboratories had a transcription-e
rror rate of up to 39% and an error rate of up to 26% for analytical r
esults. The worst-performing laboratory had errors (of patient identif
ication or results of analysis) in 46% of requests. The three best-per
forming laboratories achieved 85% error-free reporting, with one achie
ving 95%. Conclusions: Error rates in Australian pathology laboratorie
s vary widely, but may be as high as 46% for all specimens in some lab
oratories. The types of errors reported were under the control of the
laboratory, and would affect the accuracy of reported pathology test r
esults, with potential adverse outcomes for patient care and inefficie
nt use of health-care resources. There is a need to establish broader
quality assurance programs and performance requirements to reduce thes
e types of error.