REGRESSION OF RUBEOSIS IRIDIS AFTER TRABECULECTOMY COMBINED WITH MITOMYCIN-C

The authors report two cases in which severe rubeosis iridis regressed after trabeculectomy with intraoperative application of mitomycin-C. Several days after the operation, the vessels were no longer perfused. Only white, empty, ''ghost'' vessels were visible. This phenomenon wa s observed in one case with well-controlled intraocular pressure (IOP) after surgery, as well as in a case in which IOP rose again to high p reoperative values. The authors conclude that the regression of the ru beosis may be caused by a local, intraocular pharmacologic side effect of mitomycin-C, not by the drop in IOP alone.