MAPPING THE HOMOLOG OF THE HUMAN RB1 GENE TO CHROMOSOME-14 OF HIGHER PRIMATES

Authors
VERMA RS RAMESH KH SAMONTE RV CONTE RA
Citation
Rs. Verma et al., MAPPING THE HOMOLOG OF THE HUMAN RB1 GENE TO CHROMOSOME-14 OF HIGHER PRIMATES, Mammalian genome, 7(8), 1996, pp. 591-592
Citations number
8
Categorie Soggetti
Biology,"Genetics & Heredity","Biothechnology & Applied Migrobiology
Journal title
Mammalian genome → ACNP
ISSN journal
09388990
Volume
7
Issue
8
Year of publication
1996
Pages
591 - 592
Database
ISI
SICI code
0938-8990(1996)7:8<591:MTHOTH>2.0.ZU;2-X
Abstract
The Rb1 gene has been implicated with retinoblastoma and is located on human Chromosome (Chr) 13q14.2. A unique sequence human Rbl cosmid DN A probe has been used to localize this region on apes' Chr 14 by the F ISH technique. The conservation of the Rb] gene in higher primates at the corresponding equivalent chromosome locus (14q14) of the human may serve as a phylogenetic marker to further trace the evolutionary path way of human descent.