ALLYLBORATION AND CYCLIZATION OF 3,4-DIHYDROISOQUINOLINE DERIVATIVES - SYNTHESIS OF THE BENZOPYRROCOLINE SYSTEM

Authors
BUBNOV YN ZYKOV AY IGNATENKO AV MIKHAILOVSKY AG SHKLYAEV YV SHKLYAEV VS
Citation
Yn. Bubnov et al., ALLYLBORATION AND CYCLIZATION OF 3,4-DIHYDROISOQUINOLINE DERIVATIVES - SYNTHESIS OF THE BENZOPYRROCOLINE SYSTEM, Russian chemical bulletin, 45(4), 1996, pp. 890-892
Citations number
13
Categorie Soggetti
Chemistry
Journal title
Russian chemical bulletin → ACNP
ISSN journal
10665285
Volume
45
Issue
4
Year of publication
1996
Pages
890 - 892
Database
ISI
SICI code
1066-5285(1996)45:4<890:AACO3D>2.0.ZU;2-D
Abstract
A novel approach to hexahydropyrrolo[2,1-a]isoquinolines (hexahydroben zo[g]pyrrocolines) based on the allylboration of 3,4-dihydroisoquinoli nes followed by closure of the pyrrolidine ring through the hydroborat ion - oxidation - intramolecular N-alkylation sequence was developed.