The purpose of this study was to determine the optimal stimulation sit
e and parameters that result in the greatest changes in cutaneous bloo
d flow during dorsal column stimulation (DCS). Laser Doppler flowmetry
was used to assess cutaneous blood flow changes in both rat hindpaws
during DCS with a unipolar ball electrode. We found that stimulating t
he dorsal column at the L(2) spinal segment at 0.6 mA at either 25 or
50 Hz with a pulse duration of 0.2 ms resulted in the largest cutaneou
s blood flow increases in the rat hindpaw. In addition, the DCS respon
se appeared to be limited primarily to the hindpaw ipsilateral to the
site of DCS.