A. Walkerdeemin et al., DETECTION OF CIRCULATING ANTIGENS IN GABONESE PATIENTS WITH LOA LOA FILARIASIS, TM & IH. Tropical medicine & international health, 1(6), 1996, pp. 772-778
Circulating antigens were detected in sera of Gabonese patients with L
oa loa filarial infection by co-electrosyneresis (Co-ES). The serum sa
mples selected for this study were exposed to rabbit hyperimmune antif
ilarial antisera and human immune antisera: specific arcs were observe
d in 35/60 filarial patients, of whom 24/47 were microfilaraemic and 1
1/13 amicofilaraemic. The identity of rabbit-hyperimmune antisera and
loiasial immune sera was confirmed by the continuity of precipitation
arcs. These preliminary studies were carried out to develop diagnostic
tools for loiasis and to study the physiopathology of immune complexe
s.