A. Massawe et al., ASSESSMENT OF MOUTH-TO-MASK VENTILATION IN RESUSCITATION OF ASPHYXIC NEWBORN BABIES - A PILOT-STUDY, TM & IH. Tropical medicine & international health, 1(6), 1996, pp. 865-873
The aim of the study was to compare the effectiveness of mouth-to-mask
ventilation (MM) in neonatal asphyxia with bag-and-mask ventilation (
BM). A new mouth-to-mask infant resuscitation system was constructed.
The study was performed in two university clinics with different resou
rces. The KEM Hospital in Bombay was well equipped and neonatologists
took part in all resuscitations; Muhimbili Medical Centre in Dar es Sa
laam was understaffed and had no physicians available at resuscitation
. Therefore, different protocols had to be used. In Bombay, the study
period was limited to 5 minutes. If needed, mask ventilation was then
replaced by intubation. In Dar es Salaam, MM ventilation was continued
for up to 10 minutes, the inspiratory pressure was adjusted to 30 cmH
(2)O and the ventilation was slow (8-10 breaths/min). In Bombay, 30 ba
bies were allocated to the BM and 24 to the MM groups. In Dar es Salaa
m 56 were in the BM and 64 in the MM groups. The results for term babi
es in Bombay and both term and pre-term babies in Dar es Salaam showed
no significant differences between the two groups of treatment, as de
termined by Apgar score greater than or equal to 4 at 5 and 10 minutes
, number of babies with their first gasp, heart rate >130 beats/min or
pulse oximeter values above 75%, all at 5 minutes. An Apgar score gre
ater than or equal to 4 at 5 minutes was achieved in more than 75% of
all infants, irrespective of treatment. The rates of early neonatal mo
rtality and neonatal convulsions did not differ between the two method
s of resuscitation. In Dar es Salaam, the low respiratory frequency us
ed in both groups was associated with a slow increase in heart rate ab
ove 130 beats per min. This result indicates that further studies wilt
be needed before such slow respiratory frequencies are used. We concl
ude that, if adequate training is provided and the respiratory frequen
cy is kept within the normal range, MM ventilation is an alternative t
o assisted ventilation when no bag and mask is available. However, fur
ther studies are necessary, since this method has proved to be tiring
and uncomfortable for the resuscitating health personnel.