TRICHORZIANINS ACTIVITY ON MYCELIAL GROWT H OF SCLEROTIUM-CEPIVORUM UNDER LABORATORY CONDITIONS IN-VITRO

Peptidic secondary metabolites, trichorzianins, obtained from Trichode rma harzianum inhibited mycelial growth of Sclerotium cepivorum. Bioss ays showed the inhibitory activity of the crude natural trichorzianin mixture causing up to 100% at 500 mu g.ml(-1). Silica gel chromatograp hy resolved this mixture in two groups, trichorzianins TA neutral and trichorzianins TB acidic that had different inhibitory activities on m ycelial growth of S. cepivorum. The mixture of trichorzianins had high er activity than TA and TB separately, suggesting a synergistic effect on the inhibition of mycelial growth.