Objetive: To assess the diagnostic accuracy of laparoscopy in the stud
y of patients with ascites of unknown cause, and the frequency of lapa
roscopy use for that indication after the advent of ultrasonography an
d computed tomography. Design: A retrospective study of 4.536 laparosc
opies performed in 16 years, in two periods of 8 years, and the correl
ation with the pathologic diagnosis, Patients: 137 patients in whom la
paroscopy was indicated for the study of ascites of unkown cause. Resu
lts: 63.5% of laparoscopies were performed over the first 8-year perio
d, and 36.5% in the second (p = 0.0001), and for the study of ascites
2.6 and 3.8% respectively, Laparoscopy and biopsy were diagnostic in 9
8.5% of cases; 51% carcinomatosis, 17.5% liver cirrhosis, 11.7% hepati
c neoplasm and others. Two of five cases of peritoneal tuberculosis we
re considered carcinomatosis at laparoscopy, There were no serious com
plications, Conclusions: The advent of new imaging method has reduced
the use of laparoscopy, although it is still employed frequently for t
he study of ascites. Laparoscopy with biopsy when necesary has an exce
llent effectiveness and accuracy for the diagnosis of ascites of unkno
wn cause.