Aflatoxins are metabolites of Aspergillus sp fungi which are contamina
nts of corn, peanut and cottonseed. Reduction of aflatoxins exposure i
s necessary to avoid disease in humans and animals. In veterinary mede
cine, the major effects of acute and sub-acute aflatoxicosis are hepat
ic necrosis and bile duct proliferation. Chronic aflatoxicosis are res
ponsible for economical losses because of slow growth and decreased fe
ed conversion efficiency. Hepatic carcinomas are also observed in some
animal species. Histopathological and biochemical events following an
imal exposure explain the aflatoxins mechanism of action.