We prospectively examined the association between alexithymia and risk
of death over an average follow-up time of nearly 5.5 years in 42- to
60-year-old men (N=2297) participating in the Kuopio Ischemic Heart D
isease Risk Factor Study (KIHD). Alexithymia, impairment in identifica
tion, processing, and verbal expression of inner feelings, was assesse
d by the validated Toronto Alexithymia Scale (TAS) In age-adjusted sur
vival analyses, men in the highest alexithymia quintile had a twofold
greater risk of all-cause death (p<0.001) and a threefold greater risk
of death from accidents, injury, or violence (p<0.02) relative to the
men in the three lowest alexithymia quintiles. There was little evide
nce for confounding by behavioral factors (smoking, alcohol consumptio
n, physical activity), physiological risk factors (LDL, HDL, body mass
index, hypertension), socioeconomic status, marital status, perceived
health, prior diseases and diagnoses, depressive symptoms or social c
onnections. Consistent and even stronger associations between alexithy
mia and all-cause death were found in a healthy subgroup (N=1650). Why
difficulties in dealing with emotions associate with increased mortal
ity remains unclear. Our findings suggest that the association is inde
pendent from the effect of well-known behavioral, biological, and psyc
hosocial risk factors. Copyright (C) 1996 Elsevier Science Inc.