Background: This study was designed to determine the incidence of fals
e-negative and false-positive results when the self-inflating bulb (SI
B) is used to differentiate tracheal from esophageal intubation in mor
bidly obese patients using two techniques. In technique 1, the SIB is
compressed before it is connected to the tube; in technique 2, the SIB
is compressed after connection to the tube. Methods: With institution
al review board approval, 54 consenting adult morbidly obese patients
(body mass index > 35) undergoing elective surgical procedures were in
cluded in the study. After anesthetic induction and muscle relaxation,
both the trachea and esophagus were intubated under direct vision wit
h identical cuffed tubes. The efficacy of the sip in verifying the pos
ition of both tubes was tested by a second anesthesiologist. The speed
of reinflation was graded as rapid (<4 s) or none (>4 s), using both
techniques. In the case of tracheal intubation, the absence of reinfla
tion was recorded as a false-negative, whereas in cases of esophageal
intubation, rapid reinflation was recorded as a false-positive. Identi
fication of tube location by the second anesthesiologist was based on
SIB reinflation results from techniques 1 and 2, as well as the presen
ce of a flatuslike sound elicited by technique 2 in esophageally place
d tubes. All patients were retested by the SIB after receiving three b
reaths of 400-500 ml each. In all patients exhibiting false-negative r
esults, six obese patients exhibiting true-positive results, and four
nonobese patients exhibiting true-positive results, tracheal responses
to the SIB maneuvers were observed directly by a flexible fiberoptic
bronchoscope incorporating an airtight system, 15-20 min after mechani
cal ventilation was instituted. Results: The incidence of false-negati
ve results was initially 30% with technique 1 and 11% with technique 2
, but decreased to 4% when technique 2 was used after the delivery of
three breaths. The second anesthesiologist initially identified tube l
ocation in 92.5% of patients correctly. After the delivery of three br
eaths, tube location was correctly identified in 96.3% of patients. Fi
beroptic bronchoscopic examination of the patients exhibiting false-ne
gative results revealed exaggerated inward bulging of the posterior tr
acheal membrane during reinflation of the SIB when technique 1 was use
d. Conclusions: Contrary to previous investigations in healthy patient
s, the current study demonstrates a high incidence of false-negative r
esults when the SIB is used to confirm tracheal intubation in morbidly
obese patients. If the SIB is used, the technique should include comp
ression of the SIB after connection to the tube and should be used in
conjunction with other clinical signs and technical aids. The mechanis
m of false-negative results in these patients seems to be related to r
eduction of caliber of airways secondary to a marked decrease in funct
ional residual capacity, and collapse of large airways due to invagina
tion of the posterior tracheal wall when subatmospheric pressure is ge
nerated by the SIB.