CHARGED CYCLODEXTRIN DERIVATIVES AS CHIRAL SELECTORS IN CAPILLARY ELECTROPHORESIS

This review summarizes recent developments in chiral capillary electro phoresis using charged cyclodextrins as chiral selectors and shows the possibilities of separation of enantiomers of the basic chiral analyt es using an extremely low concentration of chiral selector as well as enantioseparation of neutral chiral analytes in capillary electrokinet ic chromatography, enantioseparation in counter current flow of chiral selector and solute and several new possibilities for the reversal of enantiomer migration order. The usefulness of NMR spectroscopy is als o shown for the better understanding of the mechanism of chiral separa tion in CE.