PERIPHERAL NEUROEPITHELIOMA (PERIPHERAL PRIMITIVE NEUROECTODERMAL TUMOR) OF THE UTERINE CERVIX

We report here a case of peripheral neuroepithelioma arising in the ut erine cervix. A 44-year-old female had complained of irregular genital bleeding for several months and was diagnosed as extraosseous Ewing's sarcoma (EOE) from biopsy specimens initially. The tumor cells, which were intensely stained by periodic acid-Schiff (PBX) and digested wit h diastase, were uniformly small and round, had hyperchromatic nuclei and scant, indistinct cytoplasm. The surgically-removed tumor cells we re immunohistochemically stained with antisera against neuro-specific enolase (NSE), tyrosine hydroxylase. In ultrastructural study, neurose cretory granules mere observed. Finally we diagnosed this case as peri pheral neuroepithelioma(peripheral primitive neuroectodermal tumor; PN ET).