MODELIZATION, SYNTHESIS AND ANTIVIRAL EVALUATION OF NEW 2,3-DISUBSTITUTED THIAZOLIDINONE NUCLEOSIDE ANALOGS

Authors
GRACIET JC NIDDAM V GAMBERONI M TRABAUD C DESSOLIN J MEDOU M MOURIER N ZOULIM F BOREL C HANTZ O CAMPLO M CHERMANN JC KRAUS JL
Citation
Jc. Graciet et al., MODELIZATION, SYNTHESIS AND ANTIVIRAL EVALUATION OF NEW 2,3-DISUBSTITUTED THIAZOLIDINONE NUCLEOSIDE ANALOGS, Bioorganic & medicinal chemistry letters, 6(15), 1996, pp. 1775-1780
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
6
Issue
15
Year of publication
1996
Pages
1775 - 1780
Database
ISI
SICI code
0960-894X(1996)6:15<1775:MSAAEO>2.0.ZU;2-9
Abstract
The syntheses, anti-HIV and anti-HBV in vitro evaluations of new thiaz olidinone nucleoside analogues are described. Preliminary molecular mo deling studies demonstrated that these new analogues conserved the ess ential elements of the hypothesized biological active synthon.(1) Copy right (C) 1996 Elsevier Science Ltd