ACETYLCHOLINESTERASE AMPEROMETRIC DETECTION SYSTEM BASED ON A COBALT(II) TETRAPHENYLPORPHYRIN-MODIFIED ELECTRODE

Authors
DENG Q DONG SJ
Citation
Q. Deng et Sj. Dong, ACETYLCHOLINESTERASE AMPEROMETRIC DETECTION SYSTEM BASED ON A COBALT(II) TETRAPHENYLPORPHYRIN-MODIFIED ELECTRODE, Analyst, 121(8), 1996, pp. 1123-1126
Citations number
24
Categorie Soggetti
Chemistry Analytical
Journal title
Analyst → ACNP
ISSN journal
00032654
Volume
121
Issue
8
Year of publication
1996
Pages
1123 - 1126
Database
ISI
SICI code
0003-2654(1996)121:8<1123:AADSBO>2.0.ZU;2-Y
Abstract
An acetylcholinesterase (AChE) activity detection system was fabricate d based on the electrocatalysis of cobalt(II) tetraphenylporphyrin of the electrooxidation of thiocholine chloride, which is the product of the hydrolysis of acetylthiocholine chloride by AChE. A simple modifie d method was used to form the base electrode. AChE was cross-linked on the base electrode by glutaraldehyde. The optimum working conditions are discussed and the characteristics of the detection system are eval uated.