UV-CROSS-LINKING OF THE GLOBULAR DOMAIN OF HISTONE H1 WITH DNA IN DEOXYRIBONUCLEOPROTEIN

Authors
KUROCHKINA LP KOLOMIJTSEVA GY
Citation
Lp. Kurochkina et Gy. Kolomijtseva, UV-CROSS-LINKING OF THE GLOBULAR DOMAIN OF HISTONE H1 WITH DNA IN DEOXYRIBONUCLEOPROTEIN, Biochemistry, 61(6), 1996, pp. 757-763
Citations number
27
Categorie Soggetti
Biology
Journal title
Biochemistry → ACNP
ISSN journal
00062979
Volume
61
Issue
6
Year of publication
1996
Pages
757 - 763
Database
ISI
SICI code
0006-2979(1996)61:6<757:UOTGDO>2.0.ZU;2-#
Abstract
UV-irradiated deoxyribonucleoprotein was digested with trypsin to clea ve the histones, and a cross-linked DNA-peptide complex was isolated. The globular domain of the H1 histone was found to be linked to DNA. T he resistance of this globular domain to trypsinization is discussed i n relation to chromatin structure.