In a series of 233 keratoconus cases, electroretinograms (ERGs) and vi
sual evoked responses (VERs) were recorded; the results of this study
are discussed. In six cases, the ERGs were extinguished, and the VERs
were pathologic. In contrast to this, in four cases, ERGs were normal,
but VERs were pathologic. Postoperatively the electrophysiologic find
ings remained the same, and the ophthalmoscopic examination of the eye
s revealed the existence of a diffuse tapetoretinal degeneration or a
macular lesion. These data show clearly the coexistence in many cases
of keratoconus with diffuse tapetoretinal degeneration or macular lesi
on. The preoperative value of an electrophysiologic study of keratocon
us patients is justified to avoid an unneeded corneal transplant.