Wc. Mcgarvey et al., PARTIAL ACHILLES-TENDON RUPTURES ASSOCIATED WITH FLUOROQUINOLONE ANTIBIOTICS - A CASE-REPORT AND LITERATURE-REVIEW, Foot & ankle international, 17(8), 1996, pp. 496-498
Fluoroquinolone antibiotics (such as ciprofloxacin, pefloxacin, ofloxa
cin, norfloxacin, temafloxacin, etc.) have recently been implicated in
the etiology of Achilles tendinitis and subsequent tendon rupture. We
report on a patient with bilateral partial Achilles tendon ruptures a
ssociated with ciprofloxacin therapy and present a review of the curre
nt literature on this increasingly recognized complication. Treatment
with fluoroquinolones should be discontinued at the first sign of tend
on inflammation so as to reduce the risk of subsequent rupture. Magnet
ic resonance imaging is useful in distinguishing between Achilles tend
initis and partial tendon rupture.