Mh. Phillips et al., EFFECTS OF IRRADIATION GEOMETRY ON TREATMENT PLAN OPTIMIZATION WITH LINAC-BASED RADIOSURGERY, Medical physics, 23(8), 1996, pp. 1399-1406
A comparison was made of different treatment plans to determine the ef
fect on the three-dimensional dose distributions of varying the allowe
d parameters in linac-based stereotactic radiosurgery with circular co
llimators; these parameters are are position, length, and weighting, a
nd collimator diameter. For the class of eccentrically shaped target v
olumes that are not so irregular as to require several separate isocen
ters, it was found that superior dose distributions could be achieved
by varying are length, are position, are weighting, and collimator dia
meter. An analysis of the results achieved with an automated planning
program indicates that, in general, the variables of are position and
are length are of greater importance than collimator size or beam weig
hting. However, there are cases where varying these latter two paramet
ers does result in markedly better dose distributions. A deeper invest
igation into the effects of multiple collimators on the dose distribut
ion in the area of steepest gradient demonstrated that multiple collim
ator sizes do not significantly degrade the dose falloff, which is in
fact mostly determined by the effects of intersecting arcs. (C) 1996 A
merican Association of Physicists in Medicine.