REDUCTION OF INTERSTITIAL FLUID PRESSURE AFTER TNF-ALPHA TREATMENT OF3 HUMAN-MELANOMA XENOGRAFTS

Authors
KRISTENSEN CA NOZUE M BOUCHER Y JAIN RK
Citation
Ca. Kristensen et al., REDUCTION OF INTERSTITIAL FLUID PRESSURE AFTER TNF-ALPHA TREATMENT OF3 HUMAN-MELANOMA XENOGRAFTS, British Journal of Cancer, 74(4), 1996, pp. 533-536
Citations number
20
Categorie Soggetti
Oncology
Journal title
British Journal of Cancer → ACNP
ISSN journal
00070920
Volume
74
Issue
4
Year of publication
1996
Pages
533 - 536
Database
ISI
SICI code
0007-0920(1996)74:4<533:ROIFPA>2.0.ZU;2-7
Abstract
Tumour necrosis factor-alpha (TNF-alpha) reduced the interstitial flui d pressure (IFP) to 54-64% (P<0.05) and the mean arterial blood pressu re (MABP) to 70% (P<0.01) of control values after 5 h in three human m elanoma tumour lines transplanted to nude mice.