THE GRIGNARD-REAGENT FROM 2-BROMOMETHYL-1,3-DIOXOLANE, A NOVEL AND EFFICIENT D(2)-REAGENT - SYNTHESIS OF BRANCHED-CHAIN CARBOHYDRATE-DERIVATIVES

Authors
SCHMEICHEL M REDLICH H
Citation
M. Schmeichel et H. Redlich, THE GRIGNARD-REAGENT FROM 2-BROMOMETHYL-1,3-DIOXOLANE, A NOVEL AND EFFICIENT D(2)-REAGENT - SYNTHESIS OF BRANCHED-CHAIN CARBOHYDRATE-DERIVATIVES, Synthesis, (8), 1996, pp. 1002
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
8
Year of publication
1996
Database
ISI
SICI code
0039-7881(1996):8<1002:TGF2AN>2.0.ZU;2-B
Abstract
2-Bromomethyl-1,3-dioxolane reacts readily with magnesium in tetrahydr ofuran to form the corresponding Grignard reagent, which ;can be used as a novel and efficient d(2)-synthon in organic synthesis. The unusua l stability of this reagent even allows the addition to unreactive car bohydrate ketones at elevated temperatures.