E. Bejan et al., THE REACTION OF ENAMINONES WITH CARBOXAMIDINES - A CONVENIENT ROUTE FOR THE SYNTHESIS OF POLYAZA HETEROCYCLES, Synthesis, (8), 1996, pp. 1012
A simple and efficient synthetic method to polyaza heterocyclic struct
ures containing 1,3-pyrimidine units has been developed. It is based o
n the reaction of the enaminones such as 5, 7 and 9 with the appropria
te carboxamidines under basic conditions. By this procedure several ne
w polyaza heterocycles have been prepared in good yields.