ALPHA-ARYL O-VINYL CARBAMATES - TANDEM CARBOLITHIATION-ALPHA-ALKYLATION AND CARBOLITHIATION-[1,2]-WITTIG REARRANGEMENT REACTIONS

Authors
SUPERCHI S SOTOMAYOR N MIAO GB JOSEPH B CAMPBELL MG SNIECKUS V
Citation
S. Superchi et al., ALPHA-ARYL O-VINYL CARBAMATES - TANDEM CARBOLITHIATION-ALPHA-ALKYLATION AND CARBOLITHIATION-[1,2]-WITTIG REARRANGEMENT REACTIONS, Tetrahedron letters, 37(34), 1996, pp. 6061-6064
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
34
Year of publication
1996
Pages
6061 - 6064
Database
ISI
SICI code
0040-4039(1996)37:34<6061:AOC-TC>2.0.ZU;2-9
Abstract
Efficient, one-pot carbolithiation - alpha-alkylation and -[1.2]-Witti g rearrangement processes of alpha-aryl O-vinyl carbamates 1 to branch ed benzyl O-carbamates 3 and 2-aryl-2-hydroxypropionamides 4, includin g Naproxen analogues, is described. Copyright (C) 1996 Elsevier Scienc e Ltd