BIS(AMINOPHOSPHINE)-NICKEL COMPLEXES AS EFFICIENT CATALYSTS FOR ALKYLATION OF ALLYLIC ACETATES WITH STABILIZED NUCLEOPHILES

Authors
BRICOUT H CARPENTIER JF MORTREUX A
Citation
H. Bricout et al., BIS(AMINOPHOSPHINE)-NICKEL COMPLEXES AS EFFICIENT CATALYSTS FOR ALKYLATION OF ALLYLIC ACETATES WITH STABILIZED NUCLEOPHILES, Tetrahedron letters, 37(34), 1996, pp. 6105-6108
Citations number
30
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
34
Year of publication
1996
Pages
6105 - 6108
Database
ISI
SICI code
0040-4039(1996)37:34<6105:BCAECF>2.0.ZU;2-M
Abstract
The alkylation of a variety of allylic acetates with dimethyl malonate catalysed by nickel-diphosphine complexes is reported. It is shown th at in most cases bis(aminophosphine) type ligands lead to much more ef ficient catalysts than dppb and other usual diphosphines. The use of c hiral ligands during the alkylation of 3-acetoxycyclohexene affords di methyl cyclohex-2-enylmalonate in up to 40% ee. Copyright (C) 1996 Pub lished by Elsevier Science Ltd