TREATMENT OF ACQUIRED MYASTHENIA-GRAVIS ASSOCIATED WITH THYMOMA IN 2 DOGS

Two cases of myasthenia gravis associated with thymoma are reported. B oth were female German shepherd dogs and the thymoma was surgically re sected. Aspiration pneumonia secondary to persistent megaoesophagus wa s a complication in both cases. The myasthenia gravis did not resolve, but there was a more satisfactory control of clinical signs with anti cholinesterase treatment. Corticosteroid therapy was used in one case, but the resulting polydipsia increased the incidence of regurgitation , resulting in recurrent episodes of aspiration pneumonia.