Dementia in idiopathic hypoparathyroidism is generally ascribed to hyp
ocalcemia and improves following normalization of the serum calcium le
vel. We report a 51-year-old man with severe dementia and hypoparathyr
oidism, but without serum hypocalcemia and without clinical signs of h
ypocalcemia. There was rapid and sustained improvement and normalizati
on of symptoms after therapy with 1,25-dihydroxy-cholecalciferol. We c
onclude that hypocalcemia is not the sole cause of dementia in idiopat
hic hypoparathyroidism.