SELECTIVE ATROPHY OF TYPE-1 MUSCLE-FIBERS IN MCARDLES-DISEASE

Authors
FELICE KJ GRUNNET ML SIMA AAF
Citation
Kj. Felice et al., SELECTIVE ATROPHY OF TYPE-1 MUSCLE-FIBERS IN MCARDLES-DISEASE, Neurology, 47(2), 1996, pp. 581-583
Citations number
6
Categorie Soggetti
Clinical Neurology
Journal title
Neurology → ACNP
ISSN journal
00283878
Volume
47
Issue
2
Year of publication
1996
Pages
581 - 583
Database
ISI
SICI code
0028-3878(1996)47:2<581:SAOTMI>2.0.ZU;2-C
Abstract
McArdle's disease is a metabolic myopathy of glycogen utilization caus ed by an absence or deficiency of myophosphorylase. The muscle biopsy features include increased deposition of subsarcolemmal glycogen and a bsent phosphorylase histochemical staining of myofibers. We report the clinical and unique pathologic findings in three cases of McArdle's d isease with prominent type 1 fiber atrophy.