CELIAC-DISEASE, EPILEPSY, AND OCCIPITAL CALCIFICATIONS - HISTOPATHOLOGICAL STUDY AND CLINICAL OUTCOME

Bye et al. in 1993 first described the pathological findings in a pati ent with celiac disease (CD), bilateral occipital calcifications, and drug-resistant epilepsy who became seizure-free after extensive occipi tal resection. We report a case with an identical anatomoclinical cond ition in which surgical removal of the circumscribed calcified lesion was ineffective and epilepsy worsened until a gluten-free diet was sta rted. The poor surgical outcome may have been due to residual epilepto genic tissue or to an unidentified secondary epileptic temporal focus. Our observation confirms the histopathological characteristics of the cerebral lesion in CD and the importance of a gluten-free diet in con trolling seizures.