Over the 6 years 1989-1994, 384 percutaneous renal biopsies were perfo
rmed, 329 on native and 55 on transplanted kidneys. Biopsy was underta
ken on a day care basis in 304 instances (79.2%). Failure to obtain 5
or more glomeruli was experienced in 23 (6.0%) of the 304 day care bio
psies. There were no significant differences in technical failure rate
s between day care patients and inpatients, local analgesia and genera
l anaesthetic, or native and transplanted kidneys, but a higher rate w
as observed in biopsies performed unaided by trainees than by experien
ced operators (P = 0.002). Six patients were detained overnight for mi
nor complications and a seventh for unrelated reasons. Two patients di
scharged on the day of biopsy despite gross haematuria were readmitted
8-10 days later with secondary haemorrhage. The complication rate of
2.6% compares favourably with published data. Few paediatric renal uni
ts currently perform day care renal biopsy, and we recommend its wider
acceptance.