A CASE OF NEONATAL BARTTERS-SYNDROME

We describe a child with a neonatal presentation of Bartter's syndrome . Unlike infants previously described with a similar clinical presenta tion, the urinary excretion rate of prostaglandin E(2) in this child w as similar to normal children and Tamm-Horsfall protein was distribute d normally in the thick ascending limb of the loop of Henle. The child failed to respond to indomethacin alone, but thrived after the additi on of the angiotensin converting enzyme inhibitor, captopril.