NEUTROPHIL-RICH KI-1-POSITIVE ANAPLASTIC LARGE-CELL LYMPHOMA PRESENTING AS A TESTICULAR MASS

Ki-1-positive large cell lymphoma is an uncommon subtype of lymphoma t hat may involve lymph nodes as well as a variety of extranodal locatio ns. To the best of our knowledge, the occurrence of such a tumor in th e testis has not been previously documented. We report a case of Ki-1- positive large cell anaplastic lymphoma presenting as a testicular mas s in a 56-year old Saudi. Immunohistochemical staining revealed positi ve staining for Ki-1 and UCHL-1, which indicated a T-cell phenotype. T his was further confirmed by polymerase chain reaction analysis, which demonstrated a monoclonal cell population with rearrangement of gamma T-cell receptor. Another interesting morphologic feature was the pres ence of large numbers of neutrophils throughout the tumor. Similar neu trophil-rich lymphomas have been described recently as a special subty pe of Ki-1-positive anaplastic large cell lymphoma.