ASCARIS-SUUM - ULTRASTRUCTURAL EFFECT OF IN-VITRO ALBENDAZOLE THERAPY

Authors
MAGAMBO JK
Citation
Jk. Magambo, ASCARIS-SUUM - ULTRASTRUCTURAL EFFECT OF IN-VITRO ALBENDAZOLE THERAPY, East African medical journal, 73(2), 1996, pp. 140-142
Citations number
8
Categorie Soggetti
Medicine, General & Internal
Journal title
East African medical journal → ACNP
ISSN journal
0012835X
Volume
73
Issue
2
Year of publication
1996
Pages
140 - 142
Database
ISI
SICI code
0012-835X(1996)73:2<140:A-UEOI>2.0.ZU;2-S
Abstract
The effect of albendazole therapy on adult Ascaris suum was examined u sing transmission electron microscopy, The drug induced prominent ultr astructural changes which included the presence of necrotic dense bodi es, myelin whorls which appeared to represent various stages of lysoso mal formation and autolysis, disruption and erosion of the microvilli. The effects were mainly confined to the central region of the intesti nal epithelial cells.