By. Aminkov, COMPARISON BETWEEN LIDOCAINE ALONE AND FENTANYL WITH LIDOCAINE FOR EPIDURAL-ANESTHESIA IN DOGS, Revue de Medecine Veterinaire, 147(11), 1996, pp. 819-824
The study was designed to evaluate the benefit of an epidural administ
ration of lidocaine/fentanyl compared with lidocaine alone. Fourteen c
linically healthy dogs were administered 0.3 ml/kg 2% lidocaine with 1
:200000 epinephrine hydrochloride, 14 received a mixture of 100 mu g f
entanyl and 0.3 ml/kg 2% lidocaine with 1:200000 epinephrine hydrochlo
ride via the same route and 7 received 100 mu g fentanyl in 0.3 ml/kg
saline with 1:200000 epinephrine hydrochloride. A significantly shorte
ned onset (p < 0.001) and a longer duration (p < 0.01) of analgesia we
re observed in the group that received the lidocaine/fentanyl mixture.
A significant decrease in mean arterial blood pressure was observed i
n dogs 45 and 60 minutes after the administration of lidocaine (p < 0.
01). In conclusion, the addition of fentanyl to lidocaine resulted in
effective analgesia with shorter time of spread and greater duration o
f the analgesic block than the local anaesthetic alone.