C. Maslinski et al., HISTAMINE IN MAMMARY-GLAND - PREGNANCY AND LACTATION, Comparative biochemistry and physiology. Section A: Comparative physiology, 116(1), 1997, pp. 57-64
Citations number
30
Categorie Soggetti
Physiology,Biology
Journal title
Comparative biochemistry and physiology. Section A: Comparative physiology
1. Histamine concentration, kistidine decarboxylase (HDC), histamine N
-methyltransferase (HMT) and transglutaminase (TG ase) activities have
been followed in mouse and guinea pig mammary gland during pregnancy
and lactation. 2. The most significant changes concerned histidine dec
arboxylase (HDC) activity and their pattern was similar for the two sp
ecies. In either species 2nd trimester of pregnancy was associated wit
h stimulation whereas early lactation was associated with reduction of
the tissue HDC activity. 3. Hormonal control of HDC is suggested on t
he basis of Variations in the enzyme activity and histamine concentrat
ion in mammary gland during estrous cycle. 4. The circumstantial evide
nce is provided indicating that histamine might be involved in pregnan
cy associated growth of mammary gland and in excretory activity of lac
tating gland. Copyright (C) 1996 Elsevier Science Inc.