GENOME RESEARCH AND EVOLUTION IN TRYPANOSOMES

Authors
DONELSON JE
Citation
Je. Donelson, GENOME RESEARCH AND EVOLUTION IN TRYPANOSOMES, Current opinion in genetics & development, 6(6), 1996, pp. 699-703
Citations number
37
Categorie Soggetti
Biology,"Cell Biology","Biothechnology & Applied Migrobiology","Genetics & Heredity
Journal title
Current opinion in genetics & development → ACNP
ISSN journal
0959437X
Volume
6
Issue
6
Year of publication
1996
Pages
699 - 703
Database
ISI
SICI code
0959-437X(1996)6:6<699:GRAEIT>2.0.ZU;2-6
Abstract
Trypanosoma brucei and Trypanosoma cruzi cause different human disease s. As strategies for immune evasion, T. brucei undergoes antigenic var iation whereas T. cruzi becomes an intracellular organism. This fundam ental difference is reflected by major differences in their genome org anizations. Recent comparisons of their gene sequences indicate that t hese two trypanosome species are highly divergent evolutionarily.