UNIQUE PRESENTATION OF CROHNS-DISEASE DURING TREATMENT OF HODGKINS-DISEASE

Although Hodgkin's disease and Crohn's disease are associated with abn ormalities in cell-mediated immunity, their co-existence in an individ ual patient is uncommon. To our knowledge, this is the first report of the clinical presentation of Crohn's disease during treatment for Hod gkin's disease. The basic immunologic mechanisms underlying these two pathologic states as well as chemotherapy-related effects are postulat ed as potential etiologic mechanisms for the codevelopment of these di seases. A brief review of the literature and basic immunologic defects associated with Crohn's disease and Hodgkin's disease are presented.