Objective: To describe the management and visual outcome of patients w
ith dislocated nuclear lens fragments. Design: Case series. Setting: R
etina service at a university-affiliated hospital in Vancouver. Patien
ts: Fifty-four consecutive patients (28 men and 26 women) with retaine
d lens fragments following phacoemulsification surgery referred for ma
nagement from May 1990 to May 1994. The patients' ages ranged from 41
to 94 (average 74) years. Results: Initial ocular findings in 52 patie
nts included moderate or severe corneal edema in 23 cases (44%), intra
ocular pressure greater than 25 mm Hg in 24 (46%), intraocular inflamm
ation in 36 (69%), retinal detachment in 2 (4%) and vitreous hemorrhag
e in 4 (8%). Of the eight patients managed conservatively with medical
therapy six (75%) regained 20/40 or better vision. The remaining 46 p
atients underwent pars plana vitrectomy. The final visual acuity in th
is group was 20/40 or better in 30 patients (65%), 20/50 to 20/100 in
8 (17%) and 20/200 or worse in 8 (17%). Patients who had an anterior c
hamber intraocular lens (IOL) implanted at cataract surgery had a sign
ificantly poorer visual outcome than those who received a posterior ch
amber IOL at vitrectomy (I, = 0.03).Conclusions: When a significant se
gment of nucleus has dislocated during phacoemulsification surgery, vi
gorous irrigation or direct attempts to remove the lens fragments shou
ld be avoided, Anterior vitrectomy should be performed, and if adequat
e capsular support remains, a posterior chamber IOL should be inserted
into the ciliary sulcus.