We evaluated risk factors for functional ovarian cysts using data from
a case-control study conducted in Milan. Cases were 68 women with his
tologically confirmed functional cysts. Controls were 272 women admitt
ed to hospital for acute conditions. Compared with women who were 11 y
ears of age or younger at menarche, women who experienced menarche at
12-13 years or at 14 years or later had odds ratios (ORs) of 0.9 [95%
confidence interval (CI)=0.5-1.6] and 0.4 (95% CI=0.2-0.9). In compari
son with women reporting menstrual cycles lasting less than 26 days, t
he OR was 1.8 (95% CI=0.7-5.0) in women reporting cycles lasting 26-30
days, 1.8 (95% CI=0.4-7.4) in those reporting cycles greater than 30
days, and 1.9 (95% CI=0.4-7.7) in those with totally irregular cycles.
Body mass was inversely related to the risk of functional ovarian cys
ts: compared with women with a Quetelet index below 20, the OR was 0.9
(95% CI=0.5-1.7) in those with an index in the range from 20-24 and 0
.5 (95% CI=0.2-1.2) in those with an index of 25 or more. We found lit
tle relation between the risk of functional ovarian cysts and educatio
n, smoking, marital status, or age at first marriage. For oral contrac
eptive use, we found an OR of 1.3 (95% CI=0.7-2.6).