Controversy exists as to whether the unipolar or bipolar electrode con
figuration is superior in detecting local activations during cardiac m
apping studies. However, the strengths and weaknesses of each mode sug
gest that they may provide complementary information. To examine the r
elative merits of unipolar and bipolar electrode configurations, recor
dings by each were simultaneously acquired during episodes of ventricu
lar tachycardia in eight consecutive patients undergoing map guided ar
rhythmia surgery. Unipolar electrograms were classified as either unam
biguous or ambiguous according to whether or not they were polyphasic
in nature. The activation times from the unambiguous electrograms were
compared with activation times from the corresponding bipolar signals
where local activation was measured both at the signal's peak amplitu
de (BI-PK), and at the point at which the waveform's first major, rapi
d transient crossed baseline (BI-TRN). Occurrences of discrete diastol
ic activations were also quantified from the unipolar and bipolar trac
ings. From a total of 415 unipolar electrograms, 301 unambiguous signa
ls were identified as suitable for comparison with the bipolar signals
. Both BI-PK and BI-TRN criteria for the determination of local activa
tion were highly correlated with and not significantly different from
the local activation from the unipolar electrogram. From 85 ambiguous
unipolar electrograms, it was possible to determine local activation f
rom the corresponding bipolar signal in 33% of the occurrences. From t
he eight patients, 64 diastolic potentials were recorded of which 42 w
ere seen only in bipolar mode, 7 in only unipolar mode, and 15 were ev
ident in both tracings. The prevalence of diastolic potentials was sig
nificantly greater in recordings made using bipolar mode. The results
demonstrate that complementary information regarding local activations
and diastolic potentials can be derived from unipolar and bipolar rec
ordings and suggest that both electrode configurations should be used
in multichannel cardiac mapping systems.