Background In contrast to photorefractive keratectomy (PRK), the corne
al epithelium and Bowman's layer are preserved in LASIK. Thus, there s
hould be less scarring and regression after LASIK than after PRK. Pati
ents Between December 1993 and October 1995, we treated 113 eyes (66 p
atients). The Automated Corneal Shaper and the Keracor 116 excimer las
er were used. We evaluated refraction, visual acuity and corneal topog
raphy. Results To date, 61 eyes reached six months follow up. Mean pre
operative refraction was -14.3 D (-3.3 to -29 D: SD = 7). Mean deviati
on from target fraction was -1.4 D (-9.5 to +2.5 D; SD = 2,7) at six m
onths, 34% were within +/-0.5 D of target refraction, 46% within +/-1
D, 67% within +/-2 D, and 82% within +/-3 D. Mean change of refraction
(''regression'') from one to six months postoperatively was +0.13 D (
-7.5 to +8 D; SD = 2,1). Refractive change was <0.5 D in 51%, <1 D in
66%, <2 D in 84%, and <3 D in 89%. In 88% of eyes, the corneal interfa
ce was not or just barely visible, while it was clearly visible in 12%
. No scars were observed. Conclusions Our results indicate that LASIK
is an effective procedure in the correction of high myopia. The incide
nce of scar formation and regression is considerably lower than after
PRK.