Aj. Saxon et al., PRETREATMENT CHARACTERISTICS, PROGRAM PHILOSOPHY AND LEVEL OF ANCILLARY SERVICES AS PREDICTORS OF METHADONE-MAINTENANCE TREATMENT OUTCOME, Addiction, 91(8), 1996, pp. 1197-1209
Predictors of methadone maintenance treatment outcome have not been ex
tensively studied as they relate to variations in program philosophy,
nor have such predictors received much examination among recently trea
ted, older cohorts of opioid addicts for whom drug use patterns have c
hanged. Predictors of outcome were examined at 18 months post-treatmen
t entry for 353 admissions to methadone maintenance who received rando
m assignment to one of three counseling conditions: (1) medication onl
y, (2) standard counseling and (3) enhanced services; and one of two c
ontingency conditions: (1) no contingencies, and (2) contingency contr
acting in a six-cell 3 x 2 design. Subjects in contingency contracting
conditions were placed on contingency contracts for positive urine to
xicology results and ultimately discharged for unremitting drug use. A
ll subjects completed the Addiction Severity Index (ASI) and provided
weekly urine specimens. Predictors of urinalysis results and treatment
retention were determined using bivariate and multivariate techniques
. Interactions between subject characteristics by experimental conditi
on assignment were also examined as predictors. Higher rates of total
positive urine specimens were predicted by younger age, greater pre-tr
eatment frequency of smoking cocaine, lower ASI psychiatric composite
scores, and higher ASI legal composite scores. Higher rates of opiate
positive specimens were predicted by younger age, lower pre-treatment
frequency of alcohol intoxication, higher ASI legal and lower ASI empl
oyment and psychiatric composite scores, and assignment to medication
only/no contingencies condition. Higher rates of cocaine positives wer
e predicted by younger age, black race, lower ASI psychiatric composit
e score, greater pre-treatment frequency of intravenous and smoked coc
aine use, less pre-treatment frequency of marijuana use, and lower met
hadone dose level. Assignment to enhanced/contingency contracting pred
icted lower rates of cocaine positives. Treatment retention was predic
ted by older age, non-black race, lower ASI legal composite score, hig
her methadone dose level and assignment to non-contingent conditions.
While subject variables over which treatment providers have little con
trol were, thus, related to outcome, type of treatment provided and me
thadone dose also influenced outcome.